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| Name | W | L | SV | ERA | G | GS | IP | HA | R | ER | HR | BB | K | WHIP | OAVG | BABIP | WAR |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Jose H. Vasquez RP | 0 | 0 | 0 | 0.00 | 7 | 0 | 9.2 | 5 | 0 | 0 | 0 | 2 | 10 | 0.72 | .161 | .238 | 0.2 |
| John Williams RP | 1 | 0 | 0 | 1.13 | 8 | 0 | 8.0 | 4 | 1 | 1 | 0 | 5 | 8 | 1.13 | .138 | .190 | 0.1 |
| Gavin Floyd RP | 1 | 1 | 0 | 1.50 | 4 | 0 | 6.0 | 4 | 1 | 1 | 1 | 1 | 4 | 0.83 | .200 | .200 | -0.1 |
| Wendell Floranus RP | 0 | 0 | 0 | 1.90 | 13 | 0 | 23.2 | 19 | 8 | 5 | 1 | 7 | 9 | 1.10 | .221 | .228 | -0.1 |
| George Thanopoulos RP | 0 | 0 | 0 | 1.95 | 9 | 0 | 27.2 | 15 | 9 | 6 | 2 | 9 | 30 | 0.87 | .161 | .213 | 0.2 |
| Eric Marzec CL | 3 | 5 | 17 | 3.38 | 44 | 0 | 50.2 | 42 | 21 | 19 | 1 | 25 | 52 | 1.32 | .230 | .313 | 0.4 |
| Brian Schlitter RP | 2 | 3 | 1 | 3.73 | 41 | 0 | 41.0 | 52 | 17 | 17 | 4 | 10 | 30 | 1.51 | .315 | .366 | -0.1 |
| Travis Westbrook RP | 3 | 2 | 0 | 3.74 | 21 | 0 | 43.1 | 38 | 19 | 18 | 5 | 18 | 43 | 1.29 | .236 | .292 | -0.3 |
| Collin Balester RP | 5 | 9 | 0 | 4.22 | 18 | 11 | 70.1 | 87 | 44 | 33 | 4 | 20 | 39 | 1.52 | .305 | .339 | 0.4 |
| Brandon Workman SP | 6 | 4 | 1 | 4.41 | 19 | 17 | 96.0 | 98 | 54 | 47 | 7 | 25 | 63 | 1.28 | .257 | .290 | 0.7 |
| Justin Masterson SP | 2 | 3 | 0 | 4.47 | 10 | 10 | 54.1 | 53 | 32 | 27 | 2 | 19 | 47 | 1.33 | .242 | .298 | 0.7 |
| Ross Seaton SP | 5 | 10 | 0 | 4.70 | 18 | 18 | 97.2 | 110 | 55 | 51 | 6 | 20 | 70 | 1.33 | .286 | .333 | 1.1 |
| Edinson Volquez SP | 0 | 2 | 0 | 4.91 | 5 | 5 | 18.1 | 30 | 15 | 10 | 1 | 11 | 13 | 2.24 | .366 | .420 | 0.0 |
| Daniel Rosenbaum RP | 1 | 2 | 1 | 4.95 | 56 | 0 | 80.0 | 100 | 52 | 44 | 10 | 27 | 74 | 1.59 | .299 | .356 | -0.5 |
| Kenn Kasparek SP | 1 | 10 | 0 | 5.04 | 19 | 18 | 103.2 | 124 | 61 | 58 | 9 | 26 | 80 | 1.45 | .302 | .354 | 0.7 |
| P.J. Walters RP | 0 | 7 | 0 | 5.31 | 20 | 6 | 62.2 | 76 | 44 | 37 | 7 | 25 | 46 | 1.61 | .299 | .338 | -0.3 |
| Matt Harrison RP | 0 | 2 | 0 | 5.45 | 17 | 1 | 34.2 | 45 | 22 | 21 | 2 | 13 | 23 | 1.67 | .313 | .361 | 0.1 |
| Casey Fien RP | 2 | 1 | 0 | 5.50 | 17 | 0 | 18.0 | 17 | 11 | 11 | 3 | 6 | 8 | 1.28 | .270 | .269 | -0.5 |
| Bud Norris SP | 0 | 8 | 0 | 5.62 | 20 | 10 | 81.2 | 115 | 54 | 51 | 5 | 16 | 48 | 1.60 | .332 | .369 | 0.7 |
| Ty Jackson RP | 0 | 0 | 0 | 5.63 | 4 | 0 | 8.0 | 13 | 8 | 5 | 0 | 6 | 7 | 2.38 | .333 | .406 | -0.0 |
| Henderson Alvarez SP | 2 | 12 | 0 | 5.91 | 23 | 23 | 91.1 | 149 | 63 | 60 | 7 | 13 | 55 | 1.77 | .365 | .407 | 1.0 |
| Edgar A. Martinez RP | 1 | 1 | 0 | 8.00 | 6 | 0 | 9.0 | 12 | 11 | 8 | 1 | 4 | 4 | 1.78 | .300 | .306 | -0.2 |
| Andrew Naderer RP | 0 | 1 | 1 | 8.31 | 3 | 0 | 8.2 | 16 | 8 | 8 | 0 | 1 | 6 | 1.96 | .410 | .444 | 0.2 |
| Bradley Spooner RP | 0 | 1 | 1 | 9.15 | 10 | 0 | 19.2 | 35 | 20 | 20 | 4 | 5 | 15 | 2.03 | .407 | .456 | -0.4 |
| Kyle Uhrich RP | 0 | 1 | 0 | 14.73 | 5 | 1 | 3.2 | 9 | 9 | 6 | 1 | 1 | 3 | 2.73 | .450 | .500 | -0.2 |
