| Saturday, October 5th, 2019 |
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| RP Jason Grilli retires. |
| SP Alexi Ogando retires. |
| Wednesday, September 18th, 2019 |
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| Demoted DH Billy Butler to Double A St. Louis. |
| Friday, September 6th, 2019 |
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| Received 1B Robert Ramirez from Double A St. Louis. |
| Saturday, July 27th, 2019 |
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| Placed RP Jason Grilli on the 7-day disabled list, retroactive to 07/16/2019. |
| Monday, July 1st, 2019 |
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| Placed C Max Stassi on the 7-day disabled list, retroactive to 06/22/2019. |
| Friday, May 10th, 2019 |
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| Placed SS Eduardo Escobar on the 7-day disabled list, retroactive to 05/08/2019. |
| Thursday, April 25th, 2019 |
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| Demoted CF Sauris Mejia to Single A Montgomery. |
| Received SP Clay Buchholz from Outlaw Las Vegas. |
| Monday, March 25th, 2019 |
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| Received SS Elvis Andrus from Outlaw Las Vegas. |
| Thursday, February 28th, 2019 |
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| Promoted CF Denard Span to Outlaw Las Vegas. |
| Promoted RP Grant Dyer to Outlaw Las Vegas. |
| Promoted SP Nathan Eovaldi to Outlaw Las Vegas. |
| Promoted CF Sauris Mejia to Outlaw Las Vegas. |
| Promoted SP Kyle Hendricks to Outlaw Las Vegas. |
| Promoted RP Addison Reed to Outlaw Las Vegas. |
| Promoted 3B Will Craig to Outlaw Las Vegas. |
| Promoted SP Clay Buchholz to Outlaw Las Vegas. |
| Promoted SP Cody Anderson to Outlaw Las Vegas. |
| Promoted SP Mike Bolsinger to Outlaw Las Vegas. |
| Promoted SS Elvis Andrus to Outlaw Las Vegas. |
| Promoted RP Adam Ottavino to Outlaw Las Vegas. |
| Promoted CF Angel Pagan to Outlaw Las Vegas. |
